MTSS1 suppresses mammary tumor-initiating cells by enhancing RBCK1-mediated p65 ubiquitination

Cong, M; Wang, Y; Yang, Y; Lian, C; Zhuang, XQ; Li, XX; Zhang, PY; Liu, YJ; Tang, J; Yang, QF; Zhang, X; Xiong, H; Hu, RG; Hu, GH

Hu, GH (corresponding author), Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Inst Nutr & Hlth, CAS Key Lab Tissue Microenvironm & Tumor, Shanghai, Peoples R China.; Hu, RG (corresponding author), Univ Chinese Acad Sci, Shanghai Inst Biochem & Cell Biol, Innovat Ctr Cell Signaling Network, CAS Ctr Excellence Mol Cell Sci,State Key Lab Mol, Shanghai, Peoples R China.; Xiong, H (corresponding author), Huazhong Univ Sci & Technol, Tongji Hosp, Dept Oncol, Wuhan, Peoples R China.

NATURE CANCER, 2020; 1 (2): 222

Abstract

Tumor-initiating cells (TICs) are considered the culprits of cancer development and progression. Dysregulation of metastasis suppressor protein 1 (MTS......

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