Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1

Zhang, Y; Li, CC; Hu, CZ; Wu, Q; Cai, YP; Xing, SG; Lu, H; Wang, L; Huang, D; Sun, LC; Li, TT; He, XP; Zhong, XY; Wang, JF; Gao, P; Smith, ZJ; Jia, WD; Zhang, HF

Jia, WD; Zhang, HF (reprint author), Univ Sci & Technol China, Affiliated Hosp USTC 1, Anhui Key Lab Hepatopancreatobiliary Surg, Dept Gen Surg,Anhui Prov Hosp, Hefei, Anhui, Peoples R China.; Zhang, HF (reprint author), Univ Sci & Technol China, Sch Life

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Abstract

Lin28 plays an important role in promoting tumor development, whereas its exact functions and underlying mechanisms are largely unknown. Here, we show......

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