Metabolic mechanism and anti-inflammation effects of sinomenine and its major metabolites N-demethylsinomenine and sinomenine-N-oxide

Li, Q; Zhou, WB; Wang, YY; Kou, F; Lyu, CM; Wei, H

Wei, H (corresponding author), Shanghai Univ Tradit Chinese Med, Inst Interdisciplinary Med, Shanghai, Peoples R China.; Lyu, CM (corresponding author), Shanghai Zhulian Intelligent Technol Co Ltd, Shanghai, Peoples R China.

LIFE SCIENCES, 2020; 261 ():

Abstract

Aims: Sinomenine (SIN) is clinically used as an anti-rheumatic drug. However, the metabolic and pharmacological mechanisms of SIN combined with its me......

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