UHRF1/UBE2L6/UBR4-mediated ubiquitination regulates EZH2 abundance and thereby melanocytic differentiation phenotypes in melanoma

Kuser-Abali, G; Zhang, YF; Szeto, P; Zhao, PA; Masoumi-Moghaddam, S; Fedele, CG; Leece, I; Huang, C; Cheung, JG; Ameratunga, M; Noguchi, F; Andrews, MC; Wong, NC; Schittenhelm, RB; Shackleton, M

Shackleton, M (通讯作者),Monash Univ, Cent Clin Sch, Melbourne, Vic, Australia.;Shackleton, M (通讯作者),Alfred Hlth, Melbourne, Vic, Australia.

ONCOGENE, 2023; 42 (17): 1360

Abstract

Cellular heterogeneity in cancer is linked to disease progression and therapy response, although mechanisms regulating distinct cellular states within......

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