Aryloxypropanolamine targets amyloid aggregates and reverses Alzheimer-like phenotypes in Alzheimer mouse models

Lee, HY; Yoon, S; Lee, JH; Park, K; Jung, Y; Cho, I; Lee, D; Shin, J; Kim, K; Kim, S; Kim, J; Kim, K; Han, SH; Kim, SM; Kim, HJ; Kim, HY; Kim, I; Kim, YS

Kim, I; Kim, YS (通讯作者)，Yonsei Univ, Coll Pharm, Dept Pharm, Incheon 21983, South Korea.;Kim, I; Kim, YS (通讯作者)，Yonsei Univ, Coll Pharm, Yonsei Inst Pharmaceut Sci, Incheon 21983, South Korea.;Kim, YS (通讯作者)，Yonsei Univ, Dept Integrat Biotechnol & Translat Med, Incheon 21983, South Korea.;Kim, YS (通讯作者)，Amyloid Solut, Seongnam Si 13486, Gyeonggi Do, South Korea.

ALZHEIMERS RESEARCH & THERAPY, 2022; 14 (1):

Abstract

Background: Aggregated amyloid-beta (A beta) is considered a pathogenic initiator of Alzheimer's disease (AD), in strong association with tau hyperpho......

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