In situ triggering antitumor efficacy of alcohol-abuse drug disulfiram through Cu-based metal-organic framework nanoparticles

Hou, L; Liu, YL; Liu, W; Balash, M; Zhang, HL; Zhang, Y; Zhang, HJ; Zhang, ZZ

Zhang, Y (corresponding author), Zhengzhou Univ, Affiliated Hosp 1, Biotherapy Ctr, Zhengzhou 450052, Peoples R China.; Zhang, HJ; Zhang, ZZ (corresponding author), Zhengzhou Univ, Sch Pharmaceut Sci, Sch Pharm, Zhengzhou 450001, Peoples R China.; Zhang, HJ; Zhang, ZZ (corresponding author), Key Lab Targeting Therapy & Diag Crit Dis, Zhengzhou 450001, Peoples R China.

ACTA PHARMACEUTICA SINICA B, 2021; 11 (7): 2016

Abstract

Although approved as an alcohol-abuse drug, disulfiram (DSF) exhibited potential anticancer activity when chelated with copper (Cu). However, the low ......

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