The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies

Copin, R; Baum, A; Wloga, E; Pascal, KE; Giordano, S; Fulton, BO; Zhou, AB; Negron, N; Lanza, K; Chan, N; Coppola, A; Chiu, J; Ni, M; Wei, Y; Atwal, GS; Hernandez, AR; Saotome, K; Zhou, Y; Franklin, MC; Hooper, AT; McCarthy, S; Hamon, S; Hamilton, JD; Staples, HM; Alfson, K; Carrion, R; Ali, S; Norton, T; Somersan-Karakaya, S; Sivapalasingam, S; Herman, GA; Weinreich, DM; Lipsich, L; Stahl, N; Murphy, AJ; Yancopoulos, GD; Kyratsous, CA

Kyratsous, CA (corresponding author), Regeneron Pharmaceut Inc, Tarrytown, NY 10591 USA.

CELL, 2021; 184 (15): 3949

Abstract

Monoclonal antibodies against SARS-CoV-2 are a clinically validated therapeutic option against COVID-19. Because rapidly emerging virus mutants are be......

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