Design and synthesis of bicyclic acetals as Beta Secretase (BACE1) inhibitors

Innocenti, R; Lenci, E; Menchi, G; Pupi, A; Trabocchi, A

Trabocchi, A (reprint author), Univ Florence, Dept Chem Ugo Schiff, Via Lastruccia 13, I-50019 Florence, Italy.

BIOORGANIC & MEDICINAL CHEMISTRY, 2017; 25 (19): 5077

Abstract

Taking advantage of the structural similarity between aspartic proteases, small-molecule peptidomimetic inhibitors that already showed activity toward......

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