DNA 5-Methylcytosine-Specific Amplification and Sequencing

Liu, C; Cui, XL; Zhao, BX; Narkhede, P; Gao, YW; Liu, J; Dou, XY; Dai, Q; Zhang, LS; He, C

He, C (corresponding author), Univ Chicago, Dept Chem, Dept Biochem & Mol Biol, Chicago, IL 60637 USA.; He, C (corresponding author), Univ Chicago, Inst Biophys Dynam, Chicago, IL 60637 USA.; He, C (corresponding author), Univ Chicago, Howard Hughes Med Inst, Chicago, IL 60637 USA.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020; 142 (10): 4539

Abstract

DNA 5-methylcytosine (5mC)-specific mapping has been hampered by severe DNA degradation and the presence of 5-hydroxymethylcytosine (5hmC) using the c......

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