Multi-phaseted problems of TDP-43 in selective neuronal vulnerability in ALS

Asakawa, K; Handa, H; Kawakami, K

Asakawa, K (corresponding author), Tokyo Med Univ, Dept Biol Chem, Shinjuku Ku, Tokyo 1608402, Japan.; Asakawa, K (corresponding author), Natl Inst Genet, Div Mol & Dev Biol, 1111 Yata, Mishima, Shizuoka 4118540, Japan.; Asakawa, K (corresponding author), Grad Univ Adv Studies SOKENDAI, Dept Genet, 1111 Yata, Mishima, Shizuoka 4118540, Japan.

CELLULAR AND MOLECULAR LIFE SCIENCES, ; ():

Abstract

Transactive response DNA-binding protein 43 kDa (TDP-43) encoded by the TARDBP gene is an evolutionarily conserved heterogeneous nuclear ribonucleopro......

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