Dacomitinib-induced diarrhea: Targeting chloride secretion with crofelemer

Van Sebille, YZA; Gibson, RJ; Wardill, HR; Ball, IA; Keefe, DMK; Bowen, JM

Van Sebille, YZA (reprint author), Univ Adelaide, Adelaide Med Sch, North Terrace, Adelaide, SA 5005, Australia.

INTERNATIONAL JOURNAL OF CANCER, 2018; 142 (2): 369

Abstract

Dacomitinib, an irreversible small-molecule pan-ErbB TKI, has a high incidence of diarrhea, which has been suggested to be due to chloride secretory m......

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