ATP induces caspase-3/gasdermin E-mediated pyroptosis in NLRP3 pathway-blocked murine macrophages

Zeng, CY; Li, CG; Shu, JX; Xu, LH; Ouyang, DY; Mai, FY; Zeng, QZ; Zhang, CC; Li, RM; He, XH

He, XH (reprint author), Jinan Univ, Dept Immunobiol, Coll Life Sci & Technol, Guangzhou, Guangdong, Peoples R China.; Li, RM (reprint author), Jinan Univ, Affiliated Hosp 1, Dept Gynecol & Obstet, Guangzhou, Guangdong, Peoples R China.

APOPTOSIS, 2019; 24 (9-10): 703

Abstract

ATP acts as a canonical activator to induce NLRP3 (NOD-like receptor family, pyrin domain containing 3) inflammasome activation in macrophages, leadin......

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