Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1

Zhu, MY; Wang, H; Ding, YL; Yang, YY; Xu, Z; Shi, L; Zhang, NX

Shi, L; Zhang, NX (通讯作者),Chinese Acad Sci, Analyt Res Ctr Organ & Biol Mol, Shanghai Inst Mat Med, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China.

FASEB JOURNAL, 2022; 36 (5):

Abstract

USP2 contributes to the quality control of multiple oncogenic proteins including cyclin D1, Mdm2, Aurora-A, etc., and it is a potential target for ant......

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