PML-RAR alpha interaction with TRIB3 impedes PPAR gamma/RXR function and triggers dyslipidemia in acute promyelocytic leukemia

Li, K; Wang, F; Yang, ZN; Cui, B; Li, PP; Li, ZY; Hu, ZW; Zhu, HH

Hu, ZW (corresponding author), Cent South Univ, Xiangya Hosp 2, Natl Clin Res Ctr Metab Dis, Dept Metab & Endocrinol, Changsha 410011, Hunan, Peoples R China.; Zhu, HH (corresponding author), Zhejiang Univ, Affiliated Hosp 1, Dept Hematol & Inst Hematol, Zhejiang Prov Key Lab Hematol Oncol Diag & Treatm, Hangzhou 310058, Zhejiang, Peoples R China.

THERANOSTICS, 2020; 10 (22): 10326

Abstract

Although dyslipidemia commonly occurs in patients with acute promyelocytic leukemia (APL) in response to anti-APL therapy, the underlying mechanism an......

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