Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies

He, MN; Chai, Y; Qi, JX; Zhang, CWH; Tong, Z; Shi, Y; Yan, JH; Tan, SG; Gao, GF

Tan, SG; Gao, GF (reprint author), Chinese Acad Sci, Inst Microbiol b, CAS Key Lab Pathogen Microbiol & Immunol, Beijing 100101, Peoples R China.; Gao, GF (reprint author), Univ Chinese Acad Sci, Beijing 100049, Peoples R China.

ONCOTARGET, 2017; 8 (40): 67129

Abstract

Monoclonal antibody based immune checkpoint blockade therapies have achieved clinical successes in management of malignant tumors. As the first monocl......

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