Intracellular metabolism and potential cardiotoxicity of a ?-D-2?-C-methyl-2,6-diaminopurine ribonucleoside phosphoramidate that inhibits hepatitis C virus replication

Tao, SJ; Zhou, LH; Zhang, HW; Zhou, SM; Amiralaei, S; Shelton, J; Ehteshami, M; Jiang, Y; Amblard, F; Coats, SJ; Schinazi, RF

Schinazi, RF (reprint author), Emory Univ, Sch Med, Dept Pediat, E420,1760 Haygood Dr, Atlanta, GA 30322 USA.

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 0; ():

Abstract

?-D-2?-C-Methyl-2,6-diaminopurine ribonucleoside (2?-C-Me-DAPN) phosphoramidate prodrug (DAPN-PD) is a selective hepatitis C virus inhibitor that is m......

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