Original Research Failure to EGFR-TKI-based therapy and tumoural progression are promoted by MEOX2/GLI1-mediated epigenetic regulation of EGFR in the human lung cancer

Peralta-Arrieta, I; Trejo-Villegas, OA; Armas-Lopez, L; Ceja-Rangel, HA; Ordonez-Luna, MD; Pineda-Villegas, P; Gonzalez-Lopez, MA; Ortiz-Quintero, B; Mendoza-Milla, C; Zatarain-Barron, ZL; Arrieta, O; Zuniga, J; Avila-Moreno, F

Avila-Moreno, F (通讯作者)，Natl Autonomous Univ Mexico UNAM, Biomed Res Unit UBIMED, Lung Dis & Canc Epigen Lab, Fac Estudios Super FES Iztacala, Ave Barrios 1, Tlalnepantla De Baz 54090, Estado De Mexic, Mexico.

EUROPEAN JOURNAL OF CANCER, 2022; 160 (): 189

Abstract

Background: Mesenchyme homeobox-2 (MEOX2)-mediated regulation of gliomaassociated oncogene-1 (GLI1) has been associated with poor overall survival, co......

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