Upregulation of AMPK by 4-O-methylascochlorin promotes autophagy via the HIF-1 alpha expression

Seok, JY; Jeong, YJ; Hwang, SK; Kim, CH; Magae, J; Chang, YC

Chang, YC (reprint author), Catholic Univ Daegu, Res Inst Biomed Engn, Sch Med, Daegu, South Korea.; Chang, YC (reprint author), Catholic Univ Daegu, Sch Med, Dept Med, Daegu, South Korea.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018; 22 (12): 6345

Abstract

4-O-methylascochlorin (MAC) is a derivative of ascochlorin, a prenyl-phenol compound antibiotic isolated from the fungus Ascochyta viciae. MAC induces......

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