Interplay between TERT promoter mutations and methylation culminates in chromatin accessibility and TERT expression

Salgado, C; Roelse, C; Nell, R; Gruis, N; van Doom, R; van der Velden, P

van der Velden, P (corresponding author), Leiden Univ, Dept Ophthalmol, Med Ctr, Leiden, Netherlands.

PLOS ONE, 2020; 15 (4):

Abstract

The telomerase reverse transcriptase (TERT) gene is responsible for telomere maintenance in germline and stem cells, and is re-expressed in 90% of hum......

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