HMGCR inhibition stabilizes the glycolytic enzyme PKM2 to support the growth of renal cell carcinoma

Huang, JJ; Zhao, XY; Li, X; Peng, JW; Yang, WH; Mi, SL

Huang, JJ; Mi, SL (corresponding author), Tsinghua Univ, Tsinghua Shenzhen Int Grad Sch, Biomfg Engn Lab, Shenzhen, Guangdong, Peoples R China.

PLOS BIOLOGY, 2021; 19 (4):

Abstract

Renal cell carcinoma (RCC) is responsible for most cases of the kidney cancer. Previous research showed that low serum levels of cholesterol level pos......

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