Inhibition of histone H3-H4 chaperone pathways rescues C. elegans sterility by H2B loss

Zhao, RX; Zhu, ZW; Geng, RX; Jiang, XG; Li, W; Ou, GS

Ou, GS (通讯作者),Tsinghua Univ, Tsinghua Peking Ctr Life Sci, Beijing Frontier Res Ctr Biol Struct, McGovern Inst Brain Res,Sch Life Sci, Beijing, Peoples R China.;Ou, GS (通讯作者),Tsinghua Univ, MOE Key Lab Prot Sci, Beijing, Peoples R China.

PLOS GENETICS, 2022; 18 (6):

Abstract

Oncohistone mutations are crucial drivers for tumorigenesis, but how a living organism governs the loss-of-function oncohistone remains unclear. We ge......

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