Histone deacetylase inhibitor chidamide regulates the Wnt/beta-catenin pathway by MYCN/DKK3 in B-ALL

Zhao, LL; Lv, CF; Sun, LL; Li, Q; Wang, YH; Wu, M; Wang, YY; Guo, ZB; Bian, SC; Kong, DS; Lin, LL; Wang, Y; Zhou, J; Li, YH

Zhou, J (corresponding author), Southern Univ Sci & Technol Hosp, Dept Hematol, Shenzhen, Peoples R China.; Li, YH (corresponding author), Harbin Med Univ, Affiliated Hosp 1, Dept Hematol, Harbin, Peoples R China.

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Abstract

Our previous studies revealed that MYCN downregulates the expression of DKK3, activates the Wnt/beta-catenin signalling pathway at the transcriptional......

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