A transcription-independent mechanism determines rapid periodic fluctuations of BRCA1 expression

Nie, C; Zhou, XA; Zhou, JD; Liu, ZL; Gu, YY; Liu, WC; Zhan, J; Li, SW; Xiong, YD; Zhou, M; Shen, QJ; Wang, WB; Yang, EC; Wang, JD

Wang, JD (通讯作者),Peking Univ, Hlth Sci Ctr, Sch Basic Med Sci, Dept Radiat Med,Int Canc Inst,Beijing Key Lab Tumo, Beijing, Peoples R China.;Yang, EC (通讯作者),Peking Univ, Inst Syst Biomed, Sch Basic Med Sci, Dept Med Bioinformat,Hlth Sci Ctr, Beijing, Peoples R China.

EMBO JOURNAL, 2023; 42 (15):

Abstract

BRCA1 expression is highly regulated to prevent genomic instability and tumorigenesis. Dysregulation of BRCA1 expression correlates closely with spora......

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