Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia

Trevejo-Nunez, G; Elsegeiny, W; Aggor, FEY; Tweedle, JL; Kaplan, Z; Gandhi, P; Castillo, P; Ferguson, A; Alcorn, JF; Chen, K; Kolls, JK; Gaffen, SL

Trevejo-Nunez, G (reprint author), Univ Pittsburgh, Sch Med, Div Infect Dis, Pittsburgh, PA 15260 USA.

INFECTION AND IMMUNITY, 2019; 87 (11):

Abstract

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia worldwide, and interleukin-22 (IL-22) helps contain pneumococcal bur......

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