Tobacco Smoke and Inhaled Drugs Alter Expression and Activity of Multidrug Resistance-Associated Protein-1 (MRP1) in Human Distal Lung Epithelial Cellsin vitro

Selo, MA; Delmas, AS; Springer, L; Zoufal, V; Sake, JA; Clerkin, CG; Huwer, H; Schneider-Daum, N; Lehr, CM; Nickel, S; Langer, O; Ehrhardt, C

Selo, MA; Ehrhardt, C (corresponding author), Trinity Coll Dublin, Sch Pharm & Pharmaceut Sci, Dublin, Ireland.; Selo, MA; Ehrhardt, C (corresponding author), Trinity Coll Dublin, Trinity Biomed Sci Inst, Dublin, Ireland.; Selo, MA (corresponding author), Univ Kufa, Fac Pharm, Al Najaf, Iraq.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020; 8 ():

Abstract

Multidrug resistance-associated protein-1 (MRP1/ABCC1) is highly expressed in human lung tissues. Recent studies suggest that it significantly affects......

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