Preclinical profile and phase I clinical trial of a novel androgen receptor antagonist GT0918 in castration-resistant prostate cancer

Zhou, T; Xu, WD; Zhang, W; Sun, Y; Yan, HH; Gao, X; Wang, FB; Zhou, QX; Hou, JG; Ren, SC; Yang, Q; Yang, B; Xu, CL; Zhou, QQ; Wang, MY; Chen, CY; Sun, YH

Sun, YH (corresponding author), Second Mil Med Univ, Changhai Hosp, Dept Urol, 168 Changhai Rd, Shanghai 200433, Peoples R China.; Chen, CY (corresponding author), Suzhou Kintor Pharmaceut, 218 Xinghu St, Suzhou 215123, Jiangsu, Peoples R China.

EUROPEAN JOURNAL OF CANCER, 2020; 134 (): 29

Abstract

Purpose: We conducted preclinical experiments and phase I clinical trial to investigate the safety, pharmacokinetics (PK) and antitumour effects of GT......

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