Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas

Patel-Hett, S; Martin, EJ; Mohammed, BM; Rakhe, S; Sun, PL; Barrett, JC; Nolte, ME; Kuhn, J; Pittman, DD; Murphy, JE; Brophy, DF

Murphy, JE (reprint author), Pfizer Inc, Rare Dis Res Unit, Worldwide Res Dev & Med, 610 N Main St, Cambridge, MA 02139 USA.

HAEMOPHILIA, 2019; 25 (5): 797

Abstract

Introduction Tissue factor pathway inhibitor (TFPI) is an endogenous inhibitor of the extrinsic pathway that negatively regulates thrombin production ......

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