Ribosome-targeting antibacterial agents: Advances, challenges, and opportunities

Zhang, LY; He, J; Bai, L; Ruan, SH; Yang, T; Luo, YF

Yang, T; Luo, YF (corresponding author), Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Peoples R China.; Yang, T; Luo, YF (corresponding author), Sichuan Univ, West China Hosp, Canc Ctr, Collaborat Innovat Ctr Biotherapy, Chengdu 610041, Peoples R China.; Yang, T (corresponding author), Sichuan Univ, West China Hosp, Lab Human Dis & Immunotherapies, Chengdu 610041, Peoples R China.

MEDICINAL RESEARCH REVIEWS, ; ():

Abstract

Ribosomes, which synthesize proteins, are critical organelles for the survival and growth of bacteria. About 60% of approved antibiotics discovered so......

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