Practical Early Development Synthesis of Nav1.7 Inhibitor GDC-0310

Stumpf, A; St-Jean, F; Lao, D; Cheng, ZK; Angelaud, R; Gosselin, F

Stumpf, A; St-Jean, F (corresponding author), Genentech Inc, Dept Small Mol Proc Chem, 1 DNA Way, San Francisco, CA 94080 USA.

SYNTHESIS-STUTTGART, 2020; 52 (22): 3406

Abstract

The concise early development route to the Nav1.7 inhibitor GDC-0310 is described. The active pharmaceutical ingredient (API) contains one stereocente......

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