Genetic and Non-Genetic Mechanisms of Resistance to BCR Signaling Inhibitors in B Cell Malignancies

Ondrisova, L; Mraz, M

Mraz, M (corresponding author), CEITEC Masaryk Univ, Mol Med, Brno, Czech Republic.; Mraz, M (corresponding author), Univ Hosp Brno, Dept Internal Med Hematol & Oncol, Brno, Czech Republic.; Mraz, M (corresponding author), Masaryk Univ, Fac Med, Brno, Czech Republic.

FRONTIERS IN ONCOLOGY, 2020; 10 ():

Abstract

The approval of BTK and PI3K inhibitors (ibrutinib, idelalisib) represents a revolution in the therapy of B cell malignancies such as chronic lymphocy......

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