Telaglenastat plus Everolimus in Advanced Renal Cell Carcinoma: A Randomized, Double-Blinded, Placebo-Controlled, Phase II ENTRATA Trial

Lee, CH; Motzer, R; Emamekhoo, H; Matrana, M; Percent, I; Hsieh, JJ; Hussain, A; Vaishampayan, U; Liu, S; McCune, S; Patel, V; Shaheen, M; Bendell, J; Fan, AC; Gartrell, BA; Goodman, OB; Nikolinakos, PG; Kalebasty, AR; Zakharia, Y; Zhang, ZT; Parmar, H; Akella, L; Orford, K; Tannir, NM

Lee, CH (通讯作者)，Mem Sloan Kettering Canc Ctr, Genitourinary Oncol Serv, 300 E 66th St, New York, NY 10065 USA.;Tannir, NM (通讯作者)，UT MD Anderson Canc Ctr, Div Canc Med, Dept Genitourinary Med Oncol, 1155 Pressler St,Unit 1374, Houston, TX 77030 USA.

CLINICAL CANCER RESEARCH, 2022; 28 (15): 3248

Abstract

Purpose: Glutaminase is a key enzyme, which supports ele-vated dependency of tumors on glutamine-dependent biosyn-thesis of metabolic intermediates. D......

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