Toll-like receptor 4 regulates spontaneous intestinal tumorigenesis by up-regulating IL-6 and GM-CSF

Shi, YJ; Zhao, QQ; Liu, XS; Dong, SH; Ji-Fu, E; Li, X; Liu, C; Wang, H

Wang, H (reprint author), Second Mil Med Univ, Chang Hai Hosp, Dept Colorectal Surg, Shanghai 200433, Peoples R China.; Liu, C (reprint author), Second Mil Med Univ, Fac Naval Med, Dept Radiat Med, Shanghai 200433, Peoples R China.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020; 24 (1): 385

Abstract

Inflammation is as an important component of intestinal tumorigenesis. The activation of Toll-like receptor 4 (TLR4) signalling promotes inflammation ......

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