SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma

Wang, SS; You, X; Liu, XS; Zhang, FW; Zhou, HJ; Shang, XC; Cai, L

Wang, SS; Cai, L (通讯作者)，Zhejiang Univ, Affiliated Hangzhou Chest Hosp, Sch Med, Cent Lab, 208 Huancheng Dong Rd, Hangzhou 310003, Zhejiang, Peoples R China.

ISCIENCE, 2023; 26 (7):

Abstract

Drug resistance prominently hampers the effects of systemic therapy of sorafe-nib to hepatocellular carcinoma (HCC). Epigenetics have critical regulat......

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