Efficacy of the MEK Inhibitor Cobimetinib and its Potential Application to Colorectal Cancer Cells

Gong, S; Xu, DS; Zhu, JL; Zou, FD; Peng, R

Zou, FD; Peng, R (reprint author), Sichuan Univ, Coll Life Sci, Chengdu, Sichuan, Peoples R China.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018; 47 (2): 680

Abstract

Background/Aims: Mutations in the Ras/Raf/MEK/ERK pathway are detected in 50% of colorectal cancer cases and play a crucial role in cancer development......

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