Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice

Zhang, Y; Liang, BY; Song, XH; Wang, HC; Evert, M; Zhou, Y; Calvisi, DF; Tang, LL; Chen, X

Tang, LL (corresponding author), Chongqing Univ, Coll Bioengn, Key Lab Biorheol Sci & Technol, Minist Educ, 174 Shazhengjie, Chongqing 400044, Peoples R China.; Chen, X (corresponding author), Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, 513 Parnassus Ave,HSE1420, San Francisco, CA 94143 USA.

AMERICAN JOURNAL OF PATHOLOGY, 2021; 191 (5): 930

Abstract

Hepatocellular carcinoma (HCC) and hepatoblastoma are the major types of primary liver cancer in adulthood and childhood, respectively. Wnt/B-catenin ......

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