Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins

Jia, N; Patel, DJ

Jia, N; Patel, DJ (corresponding author), Mem Sloan Kettering Canc Ctr, Struct Biol Program, 1275 York Ave, New York, NY 10021 USA.; Jia, N (corresponding author), Southern Univ Sci & Technol, Sch Med, Dept Biochem, Shenzhen, Peoples R China.

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2021; 22 (8): 563

Abstract

Bacteriophage anti-CRISPR proteins evolved to counter CRISPR-Cas-mediated immunity in prokaryotes. Recent structural studies have provided novel insig......

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