A single nucleotide polymorphism-based formula to predict the risk of propofol TCI concentration being over 4 mu g mL(-1) at the time of loss of consciousness

Zheng, ZL; Xue, FL; Wang, HN; He, YQ; Zhang, LY; Ma, WD; Zhang, CB; Guan, YP; Ye, F; Wen, YZ; Li, XY; Huang, M; Huang, WQ; Wang, ZX; Li, JL

Li, JL (通讯作者)，Sun Yat sen Univ, Sch Pharmaceut Sci, Inst Clin Pharmacol, Guangzhou, Guangdong, Peoples R China.;Li, JL (通讯作者)，Sun Yat sen Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Design & Evaluat, Guangzhou, Guangdong, Peoples R China.;Wang, ZX (通讯作者)，Sun Yat Sen Univ, Affiliated Hosp 1, Dept Anaesthesiol, Guangzhou, Guangdong, Peoples R China.

PHARMACOGENOMICS JOURNAL, 2022; 22 (2): 109

Abstract

We aim to develop a formula based on single nucleotide polymorphisms (SNPs) to predict whether the propofol target-controlled infusion (TCI) concentra......

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