B2M and JAK1/2-mutated MSI-H Colorectal Carcinomas Can Benefit From Anti-PD-1 Therapy

Zhang, CZ; Li, DD; Xiao, BY; Zhou, C; Jiang, W; Tang, JH; Li, Y; Zhang, RX; Han, K; Hou, ZL; Zhang, LJ; Sui, QQ; Liao, L; Pan, ZZ; Zhang, XS; Ding, PR

Ding, PR (通讯作者)，Sun Yat Sen Univ, Ctr Canc, State Key Lab Oncol South China, Collaborat Innovat Ctr Canc Med, Guangzhou 510060, Guangdong, Peoples R China.

JOURNAL OF IMMUNOTHERAPY, 2022; 45 (4): 187

Abstract

beta 2-microglobulin (B2M) and Janus kinases 1 and 2 (JAK1/2) mutations have been suggested as genetic mechanisms of immune evasion for anti-programme......

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