Phosphorylation of PPDPF via IL6-JAK2 activates the Wnt/β-catenin pathway in colorectal cancer

Zi, YY; Liu, LY; Gao, J; Xu, X; Guan, YD; Rong, ZX; Cao, Z; Li, MW; Zeng, ZM; Fan, Q; Tang, FY; He, JJ; Feng, D; Chen, JH; Dai, YD; Huang, YF; Nie, YJ; Pei, HP; Cai, QP; Li, Z; Sun, LQ; Deng, YZ

Deng, YZ (通讯作者)，Shanghai Jiao Tong Univ, Shanghai Chest Hosp, Shanghai Inst Thorac Oncol, Sch Med, Shanghai, Peoples R China.;Li, Z; Sun, LQ; Deng, YZ (通讯作者)，Cent South Univ, Xiangya Hosp, Key Lab Mol Radiat Oncol, Changsha, Peoples R China.;Li, Z; Sun, LQ (通讯作者)，Hunan Int Sci & Technol Collaborat Base Precis Med, Changsha, Peoples R China.;Cai, QP (通讯作者)，Tongji Univ, Shanghai East Hosp, Sch Med, Dept Gen Surg, Shanghai, Peoples R China.

EMBO REPORTS, 2023; 24 (9):

Abstract

Inflammation plays an important role in the initiation and progression of colorectal cancer (CRC) and leads to beta-catenin accumulation in colitis-re......

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