Multicomponent Conjugates of Anticancer Drugs and Monoclonal Antibody with PAMAM Dendrimers to Increase Efficacy of HER-2 Positive Breast Cancer Therapy

Marcinkowska, M; Stanczyk, M; Janaszewska, A; Sobierajska, E; Chworos, A; Klajnert-Maculewicz, B

Klajnert-Maculewicz, B (reprint author), Univ Lodz, Fac Biol & Environm Protect, Dept Gen Biophys, Pomorska 141-143, PL-90236 Lodz, Poland.; Klajnert-Maculewicz, B (reprint author), Leibniz Inst Polymerforsch Dresden eV, Hohe Str 6, D-01069 Dresden, Germa

PHARMACEUTICAL RESEARCH, 2019; 36 (11):

Abstract

Purpose Conjugation of nanocarriers with antibodies that bind to specific membrane receptors that are overexpressed in cancer cells enables targeted d......

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