Synthesis of 4-O-(4-amino-4-deoxy-fi-D-xylopyranosyl)paromomycin and 4-S-(fi-D-xylopyranosyl)-4-deoxy-4'-thio-paromomycin and evaluation of their antiribosomal and antibacterial activity

Mohamad-Ramshan, R; Ande, C; Matsushita, T; Haldimann, K; Vasella, A; Hobbie, SN; Crich, D

Crich, D (通讯作者),Univ Georgia, Dept Pharmaceut & Biomed Sci, 250 West Green St, Athens, GA 30602 USA.

TETRAHEDRON, 2023; 135 ():

Abstract

The design, synthesis and antiribosomal and antibacterial activity of two novel glycosides of the ami-noglycoside antibiotic paromomycin are described......

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