Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia

Mueller, KT; Waldron, E; Grupp, SA; Levine, JE; Laetsch, TW; Pulsipher, MA; Boyer, MW; August, KJ; Hamilton, J; Awasthi, R; Stein, AM; Sickert, D; Chakraborty, A; Levine, BL; June, CH; Tomassian, L; Shah, SS; Leung, M; Taran, T; Wood, PA; Maude, SL

Mueller, KT (reprint author), Novartis Inst BioMed Res, One Hlth Plaza, E Hanover, NJ 07936 USA.

CLINICAL CANCER RESEARCH, 2018; 24 (24): 6175

Abstract

Purpose: Tisagenlecleucel is an anti-CD19 chimeric antigen receptor (CAR19) T-cell therapy approved for the treatment of children and young adults wit......

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