Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway

Li, M; Xu, CF; Shi, JP; Ding, JX; Wan, XY; Chen, DH; Gao, JG; Li, CX; Zhang, J; Lin, YM; Tu, ZH; Kong, XN; Li, YM; Yu, CH

Li, YM; Yu, CH (reprint author), Zhejiang Univ, Coll Med, Affiliated Hosp 1, Dept Gastroenterol, Hangzhou 310003, Zhejiang, Peoples R China.

GUT, 2018; 67 (12): 2169

Abstract

Objective Accumulation of free fatty acids (FFAs) in hepatocytes induces lipotoxicity, leading to nonalcoholic fatty liver disease (NAFLD). This study......

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