DNA phosphorothioate modification-a new multi-functional epigenetic system in bacteria

Wang, LR; Jiang, SS; Deng, ZX; Dedon, PC; Chen, S

Chen, S (reprint author), Wuhan Univ, Sch Pharmaceut Sci, 185 Donghu Rd, Wuhan 430071, Hubei, Peoples R China.; Chen, S (reprint author), Wuhan Univ, Zhongnan Hosp, 185 Donghu Rd, Wuhan 430071, Hubei, Peoples R China.

FEMS MICROBIOLOGY REVIEWS, 2019; 43 (2): 109

Abstract

Synthetic phosphorothioate (PT) internucleotide linkages, in which a nonbridging oxygen is replaced by a sulphur atom, share similar physical and chem......

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