miR-22 suppresses DNA ligase III addiction in multiple myeloma

Caracciolo, D; Di Martino, MT; Amodio, N; Morelli, E; Montesano, M; Botta, C; Scionti, F; Talarico, D; Altomare, E; Cantafio, MEG; Zuccala, V; Maltese, L; Todoerti, K; Rossi, M; Arbitrio, M; Neri, A; Tagliaferri, P; Tassone, P

Tassone, P (reprint author), Magna Graecia Univ Catanzaro, Dept Expt & Clin Med, Campus Salvatore Venuta, Catanzaro, Italy.; Tassone, P (reprint author), Temple Univ, Coll Sci & Technol, Ctr Biotechnol, Sbarro Inst Canc Res & Mol Med, Philadelphia, PA 191

LEUKEMIA, 2019; 33 (2): 487

Abstract

Multiple myeloma (MM) is a hematologic malignancy characterized by high genomic instability. Here we provide evidence that hyper-activation of DNA lig......

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