Syndecan-2 Attenuates Radiation-induced Pulmonary Fibrosis and Inhibits Fibroblast Activation by Regulating PI3K/Akt/ROCK Pathway via CD148

Tsoyi, K; Chu, SG; Patino-Jaramillo, NG; Wilder, J; Villalba, J; Doyle-Eisele, M; McDonald, J; Liu, XL; El-Chemaly, S; Perrella, MA; Rosas, IO

Rosas, IO (reprint author), Brigham & Womens Hosp, Dept Med, Div Pulm & Crit Care, 75 Francis St, Boston, MA 02115 USA.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2018; 58 (2): 208

Abstract

Radiation-induced pulmonary fibrosis is a severe complication of patients treated with thoracic irradiation. We have previously shown that syndecan-2 ......

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