Regioisomeric Family of Novel Fluorescent Substrates for SHIP2

White, G; Prior, C; Mills, SJ; Baker, K; Whitfield, H; Riley, AM; Oganesyan, VS; Potter, BVL; Brearley, CA

Brearley, CA (corresponding author), UEA, Sch Biol Sci, Norwich Res Pk, Norwich NR4 7TJ, Norfolk, England.; Oganesyan, VS (corresponding author), UEA, Sch Chem, Norwich Res Pk, Norwich NR4 7TJ, Norfolk, England.; Potter, BVL (corresponding author), Univ Oxford, Dept Pharmacol, Med Chem & Drug Discovery, Mansfield Rd, Oxford OX1 3QT, England.

ACS MEDICINAL CHEMISTRY LETTERS, 2020; 11 (3): 309

Abstract

SHIP2 (SH2-domain containing inositol 5-phosphatase type 2) is a canonical 5-phosphatase, which, through its catalytic action on PtdInsP(3), regulates......

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