Dose-dependent pharmacokinetics of midazolam in rats: influence of hepatic first-pass metabolism

Li, R; Wang, QQ; Liu, ZH; Xie, LK; Diao, ZP; Peng, Y; Wang, GJ; Sun, JG

Sun, JG (通讯作者)，China Pharmaceut Univ, Key Lab Drug Metab & Pharmacokinet, 24 Tong Jia Xiang, Nanjing 210009, Jiangsu, Peoples R China.

XENOBIOTICA, 2023; 53 (3): 184

Abstract

To characterise the dose-dependent pharmacokinetics of midazolam and evaluate the intestinal and hepatic first-pass effects on midazolam in Sprague-Da......

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