AATF/Che-1 localizes to paraspeckles and suppresses R-loops accumulation and interferon activation in Multiple Myeloma

Bruno, T; Corleone, G; Catena, V; Cortile, C; De Nicola, F; Fabretti, F; Gumenyuk, S; Pisani, F; Mengarelli, A; Passananti, C; Fanciulli, M

Fanciulli, M (通讯作者),IRCCS Regina Elena Natl Canc Inst, SAFU Lab, Dept Res Adv Diagnost & Technol Innovat, Translat Res Area, Rome, Italy.

EMBO JOURNAL, 2022; 41 (22):

Abstract

Several kinds of stress promote the formation of three-stranded RNA:DNA hybrids called R-loops. Insufficient clearance of these structures promotes ge......

Full Text Link