GIPC-Regulated IGFBP-3 Promotes HSC Migration In Vitro and Portal Hypertension In Vivo Through a beta 1-Integrin Pathway

Yaqoob, U; Luo, FH; Greuter, T; Sakrikar, NJ; Sehrawat, TS; Lu, JW; Hu, X; Gao, JH; Kostallari, E; Chen, JB; Arab, JP; Martin-Mateos, R; Cao, S; Shah, VH

Cao, S; Shah, VH (corresponding author), Mayo Clin & Mayo Fdn, Gastroenterol Res Unit, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2020; 10 (3): 545

Abstract

BACKGROUND & AIMS: Transforming growth factor (TGF-beta)- induced activation of quiescent hepatic stellate cells (HSCs) and their transformation t......

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